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New light shed on who benefits most from weight-loss jabs

New light shed on who benefits most from weight-loss jabs

Summary

New research shows that people with certain genetic changes may lose more weight with drugs like Wegovy and Mounjaro, which are used to treat obesity. The study found that genes, along with factors like sex, age, and ancestry, can affect how well these weight-loss drugs work.

Key Facts

  • The study examined 15,000 people who used weight-loss drugs and also had genetic data from 23andMe.
  • Drugs like Wegovy and Mounjaro help people feel full, reducing hunger.
  • Some genetic variants make people lose more weight and can also cause side effects like nausea and vomiting.
  • People with European ancestry are more likely to have genetic changes linked to greater weight loss.
  • The study suggests women may have better weight-loss results from Mounjaro than men.
  • Other factors such as diet, physical activity, and health conditions also influence weight-loss outcomes.
  • The findings need further validation through more studies before they can be widely applied.

Source Information