Summary
A new study explains why weight-loss drugs like Ozempic work better for some people. The researchers found that genetics, or DNA, can affect how well these drugs work and what side effects people might face.
Key Facts
- The study analyzed 28,000 people using weight-loss drugs, focusing on their genetic data.
- Certain genetic variants were linked to better weight-loss results, while others were related to side effects.
- On average, some users lost 10% of their body weight, but results varied widely.
- Two key genes studied were GLP1R and GIPR, which affect how the drugs interact with the body.
- One gene variant increased the risk of nausea by 57% and vomiting by 36%.
- A different genetic variant related to GIPs raised the chance of vomiting by 83% when using tirzepatide.
- The results suggest that personalized treatment plans could be developed using genetic information, although more research is needed.
