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In rare chickenpox case, itchy blisters mushroom into large, rubbery nodules

In rare chickenpox case, itchy blisters mushroom into large, rubbery nodules

Summary

A 15-year-old girl in Nepal developed large, firm skin growths called keloids after recovering from chickenpox. These keloids grew from her chickenpox scars in multiple places on her body, a very rare reaction known as eruptive keloids.

Key Facts

  • The girl had chickenpox confirmed and was treated with the antiviral drug acyclovir.
  • After healing, five large keloids appeared on different parts of her body, including her chest, jaw, abdomen, and side.
  • Keloids are thick, rubbery skin growths caused by excessive collagen production during wound healing.
  • This case is only the sixth known report of eruptive keloids following chickenpox worldwide.
  • Keloids happen when wound healing goes wrong, especially in the phase where new tissue is formed.
  • People with darker skin are more likely to develop keloids.
  • Doctors think chickenpox may trigger signals that cause excessive tissue growth, but this is still a hypothesis.
  • Treating keloids is difficult because creating new wounds can make them worse.
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