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Overdose deaths fall for 3rd straight year, CDC data shows

Overdose deaths fall for 3rd straight year, CDC data shows

Summary

About 70,000 Americans died from drug overdoses last year, which is about 14% fewer than the previous year. This marks the third year in a row that overdose deaths have decreased, reaching levels similar to before the COVID-19 pandemic.

Key Facts

  • Overdose deaths in the U.S. dropped for the third straight year, reaching about 70,000 in 2025.
  • This total is nearly the same as the number of deaths in 2019, before the pandemic.
  • Deaths fell for several drugs, including fentanyl, cocaine, and methamphetamine.
  • Most states saw a decline in overdose deaths, but seven states, including Arizona, Colorado, and New Mexico, had increases.
  • Some possible reasons for the overall decline include more access to naloxone (a drug that can reverse overdoses), better addiction treatment, and changes to the drug supply.
  • New and stronger drugs like cyclorphine, a synthetic opioid stronger than fentanyl, are appearing in the drug market.
  • Certain veterinary sedatives like xylazine are now found in street drugs and can cause serious side effects.
  • The Trump administration has been reducing some programs aimed at lowering overdose deaths and drug-related infections.
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