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Pancreatic cancer is deadly and difficult to treat. A new pill could change that

Pancreatic cancer is deadly and difficult to treat. A new pill could change that

Summary

A new drug called daraxonrasib shows promise in treating pancreatic cancer by targeting a gene mutation common in this disease. Early trial results suggest that patients taking the drug lived nearly twice as long as those receiving standard chemotherapy.

Key Facts

  • Daraxonrasib is a pill developed by Revolution Medicines that targets the KRAS gene mutation.
  • KRAS mutations occur in over 90% of common pancreatic cancer cases.
  • The drug belongs to a class called RAS inhibitors.
  • Pancreatic cancer is very deadly, with a 3% five-year survival rate after it spreads.
  • Most patients are diagnosed after the cancer has advanced.
  • In early trials, patients taking daraxonrasib survived about 13.2 months on average.
  • This compares to 6.7 months for patients on standard chemotherapy alone.
  • Daraxonrasib was used after initial treatments, as a "second line" therapy.
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