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Trial of multi-cancer blood test among 142,000 NHS patients fails to meet main aim

Trial of multi-cancer blood test among 142,000 NHS patients fails to meet main aim

Summary

A large trial in the UK tested a new blood test called Galleri, designed to detect more than 50 types of cancer early. The study found that the test did not lower the number of advanced-stage cancer diagnoses compared to normal screening methods.

Key Facts

  • The trial involved 142,942 NHS patients aged 50 to 77 without cancer symptoms.
  • Participants gave blood samples once a year for three years, with half tested using the Galleri multi-cancer detection test.
  • The main goal was to see if the test reduced late-stage (stage 3 and 4) cancer diagnoses.
  • The trial did not meet this main goal, showing no significant reduction in advanced cancers with the Galleri test.
  • There was a 14% drop in the most advanced stage 4 cancers in the Galleri group, which some researchers found encouraging.
  • Experts caution that these results do not fully support widespread use of the test yet.
  • More data on cancer deaths will come in a few years to better understand the test’s impact.
  • Galleri is developed by Grail, a California-based company focused on early cancer detection technologies.
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