Cancer jab can eradicate entire tumours in patients, trial shows
Summary
A new cancer treatment called amivantamab showed promising results in a trial with patients whose cancer had returned or spread and did not respond to other treatments. The drug shrank tumors in over a third of patients and completely removed tumors in some cases, with few side effects.Key Facts
- The trial included 102 patients with head and neck cancer across 11 countries.
- Tumors shrank or disappeared in 43 patients; 15 had tumors completely eradicated.
- Amivantamab targets cancer cells by blocking two key proteins (EGFR and MET) and activating the immune system.
- The drug is given as a small injection under the skin every three weeks, making it easier to receive than traditional chemotherapy.
- Side effects were mostly mild to moderate, and less than 10% of patients stopped treatment due to side effects.
- The drug also showed positive results in lung cancer patients and is being tested in about 60 clinical trials for various cancers.
- One patient reported improved speech, reduced pain, and a return to normal eating after treatment.
- Results were presented at the American Society of Clinical Oncology annual meeting.
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