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Experimental pill promises new hope for deadly pancreatic cancer

Experimental pill promises new hope for deadly pancreatic cancer

Summary

A new pill named daraxonrasib has helped people with advanced pancreatic cancer live longer. In a study, patients taking the pill lived nearly twice as long as those on chemotherapy, with fewer serious side effects.

Key Facts

  • Daraxonrasib blocks a mutated protein that drives tumor growth in over 90% of pancreatic cancer cases.
  • The drug nearly doubled median survival time: 13.2 months versus 6.7 months for chemotherapy.
  • The study involved 500 patients with metastatic pancreatic cancer resistant to prior treatments.
  • Patients taking the pill reported less pain and better quality of life as tumors shrank.
  • Side effects included rash and mouth sores, which affected some patients’ ability to continue treatment.
  • The drug’s maker is Revolution Medicines, and the FDA is speeding up its approval process.
  • The FDA allows expanded access to the drug now for eligible patients.
  • Pancreatic cancer is very deadly, with about 67,000 new U.S. cases and over 52,000 deaths expected this year.
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