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New Cancer Pill Given Standing Ovation at Oncology Conference

New Cancer Pill Given Standing Ovation at Oncology Conference

Summary

A new pill called daraxonrasib, designed to treat pancreatic cancer, showed promising results by nearly doubling patient survival in a major late-stage trial. Doctors at a large cancer conference gave the drug a standing ovation after hearing about its success in blocking a protein that helps cancer grow.

Key Facts

  • Daraxonrasib targets a mutated protein called KRAS, which causes tumor growth in over 90% of pancreatic cancer cases.
  • Pancreatic cancer kills about 50,000 Americans yearly and has a very low five-year survival rate for advanced cases (3%).
  • The treatment lowers the risk of death by 60% compared to standard chemotherapy.
  • In the trial, patients using daraxonrasib lived an average of 13.2 months versus 6.6 months with chemotherapy.
  • Side effects led to stopping treatment in only 1.2% of patients taking daraxonrasib, much fewer than with chemotherapy (11.2%).
  • The results were presented at the 2026 ASCO Annual Meeting in Chicago and published in a leading medical journal.
  • Daraxonrasib is the first drug to effectively inhibit the KRAS protein across multiple genetic variants.
  • The drug was developed by Revolution Medicines, which funded the clinical study.
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