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Doctors hail drug that spares bladder cancer patients ‘life-changing’ surgery

Doctors hail drug that spares bladder cancer patients ‘life-changing’ surgery

Summary

A new drug called durvalumab has been shown to help treat aggressive bladder cancer without needing to remove the bladder. In a trial, adding durvalumab to chemotherapy and radiation lowered the chances of cancer returning and helped patients avoid major surgery.

Key Facts

  • Bladder cancer is the ninth most common cancer worldwide.
  • Advanced bladder cancer often requires surgery to remove the bladder, which affects how patients pass urine.
  • Durvalumab is an immunotherapy drug that helps the immune system find and destroy cancer cells.
  • A trial of 54 patients combined durvalumab with chemotherapy and radiation.
  • 85% of patients in the trial saw no return of cancer after treatment, compared to 60% with just chemotherapy and radiation.
  • The treatment helps preserve the bladder, which keeps patients’ daily life and independence better.
  • The trial was led by the Institute of Cancer Research, London, and funded by AstraZeneca and the University of Birmingham.
  • Experts say this approach could change standard care by offering effective treatment with fewer side effects.
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