'I've never been this good' – revolutionary immune reset puts lupus in remission
Summary
An experimental treatment has put lupus, a disease where the immune system attacks the body, into remission in early UK trials. The treatment works by changing a patient’s own immune cells to attack the faulty cells causing lupus, leading to recovery in most patients treated so far.Key Facts
- Lupus affects about 50,000 people in the UK, mostly women diagnosed as young adults.
- The disease causes joint pain, skin problems, and damage to organs like kidneys, heart, and lungs.
- Katie Tinkler, diagnosed 30 years ago, had severe lupus but is now in remission after the new treatment.
- The treatment modifies a patient’s T cells so they attack bad B cells that cause lupus.
- After treatment, the immune system “resets” as healthy B cells regrow, improving patient health.
- Katie no longer needs lupus medication and her organs have recovered.
- Of the first six patients treated, five remain in remission, and one has improved symptoms but had a flare-up after 11 months.
- The treatment was presented at the EULAR European Congress of Rheumatology.
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