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Louisiana man becomes first in state functionally cured of sickle cell disease

Louisiana man becomes first in state functionally cured of sickle cell disease

Summary

A young man from Louisiana, Daniel Cressy, became the first person in his region to be functionally cured of sickle cell disease using gene therapy. This treatment allows him to pursue his goal of becoming a commercial pilot, something previously blocked by his condition.

Key Facts

  • Daniel Cressy is 23 years old and from Metairie, Louisiana.
  • Louisiana has the highest rate of sickle cell disease cases per person in the US.
  • Sickle cell disease mainly affects African American people and can cause pain and serious health problems.
  • Cressy was denied a pilot license by the FAA because of his sickle cell disease.
  • He underwent gene editing therapy using CRISPR/Cas9 technology at Manning Family Children’s Hospital in New Orleans.
  • The therapy involved collecting his cells, sending them to Scotland for modification, then reinfusing them after chemotherapy.
  • After recovery, Cressy was declared functionally cured and rang a ceremonial bell at the hospital.
  • Cressy plans to become a commercial pilot, write a book, and create a charity to help others facing challenges.
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