Alzheimer’s Risk May Be Determined by One Daily Habit Combined With Genes
Summary
New research shows that how much you sleep may affect your risk of Alzheimer’s disease, especially if you have certain genes linked to the illness. The study found that poor sleep and specific gene variants can work together to cause brain changes years before any symptoms appear.Key Facts
- The study focused on the AQP4 gene, which helps clear waste from the brain during sleep.
- Researchers studied 351 adults in their mid-70s who showed early signs of Alzheimer’s-related protein buildup.
- People with some AQP4 gene variants lost brain volume faster if they slept less or had poor sleep quality.
- Sleep problems, like taking longer to fall asleep, were linked to changes in brain structure and thinking abilities.
- The study suggests sleep can change how genetic risk affects Alzheimer’s development over time.
- Experts say this research supports the idea that both genes and lifestyle play roles in disease risk.
- The research was published in the June 2026 issue of Alzheimer’s & Dementia.
- Scientists caution that genetic testing for Alzheimer’s based on these findings is not yet ready for medical use.
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