These scientists found Alzheimer's in their genes. Here's what they did next
Summary
Three scientists discovered they have a gene variant that greatly raises their risk of getting Alzheimer's disease. They are now taking steps to protect their brain health and are involved in research and advocacy for Alzheimer's treatments. One of them, June, is participating in a University of California study and is promoting lifestyle changes and federal funding for Alzheimer's research.Key Facts
- People with two copies of the APOE4 gene variant have a 60% chance of developing Alzheimer's by age 85.
- About 2-3% of people in the U.S. have this high-risk genetic profile, but most do not know it.
- One scientist, June, learned of her genetic risk through a 23andMe test when she was 57.
- June engaged with online communities for support and information about her condition.
- The Mediterranean diet, regular exercise, good sleep, and stress reduction are lifestyle changes that may help brain health.
- June joined a study at the University of California, San Diego, which examines the effects of mental and physical exercise on brain health.
- She advocates for more government funding for Alzheimer's research and drug development that targets people with APOE4-4.
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