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Women face hidden fertility ceiling despite donor eggs

Women face hidden fertility ceiling despite donor eggs

Summary

A new study finds that women over 49 have lower chances of successful pregnancy with donor eggs, partly due to changes in the womb lining. While donor eggs improve fertility, they do not fully reverse all age-related effects on pregnancy outcomes.

Key Facts

  • The study analyzed 1,774 women undergoing IVF with donor eggs.
  • Women aged 49 and older had about half the chance of pregnancy and live birth compared to women aged 35 to 40.
  • Miscarriage rates doubled for women 49 and older compared to those aged 35-40.
  • Age-related changes in the womb lining likely reduce pregnancy success despite young donor eggs.
  • Live birth rates were 46% for women in their 30s but dropped to 32% for those 49 or older.
  • Womb lining thickness stayed similar with age, but its quality declined.
  • Experts say donor eggs remain helpful but should not create false hope about age limits.
  • UK law has no upper age limit for IVF, but some European countries do have age restrictions.
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