How these twins' rare growth disorder could provide the key to preventing cancer
Summary
In a remote town in southern Ecuador, many people have Laron syndrome, a rare genetic disorder that stops the body from growing taller than about 1.2 meters (3.9 feet). Researchers are studying this condition because people with Laron syndrome seem to have less cancer and diabetes, and this could help develop new treatments to prevent these diseases.Key Facts
- Laron syndrome is a rare genetic condition that causes very short height due to the body’s inability to use growth hormone.
- Most of the 840 known cases worldwide live in the southern provinces of Ecuador, especially in the town of Piñas.
- The disorder was identified 60 years ago by doctor Zvi Laron.
- People with Laron syndrome have fewer cases of cancer and diabetes than others.
- Scientists hope to create drugs or diets that copy the protective effects seen in people with Laron syndrome.
- The syndrome likely originated in Indonesia thousands of years ago and spread through migration.
- Twins María Luisa and María del Cisne have the condition and support each other with shared experiences.
- A new research paper documenting all known cases is due to be published soon.
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