Viagra May Help Prevent Cancer From Spreading, Study Finds
Summary
A new study shows that sildenafil, the active ingredient in Viagra, may help stop cancer from spreading by affecting how cancer cells use cholesterol. The research used mice, human cancer cells, and data from Israeli health records, and found stronger effects when sildenafil was combined with cholesterol-lowering drugs called statins.Key Facts
- Sildenafil blocks an enzyme called PDE5, raising a molecule named cGMP.
- Higher cGMP affects a protein that moves cholesterol inside cancer cells.
- This lowers the cholesterol cancer cells need to spread to other parts of the body.
- The study used mice, human cancer cell samples, and health data from 5 million Israeli patients.
- Patients taking sildenafil had better cancer survival rates, especially when also using statins.
- Statins are drugs that reduce the body’s cholesterol production.
- Researchers say the findings are early and need human clinical trials before changing cancer treatment.
- Both sildenafil and statins are commonly used medicines, which might help future research.
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