Scientists Find Brain Change That May Predict Future Dementia
Summary
A new study with over 45,000 participants found that changes in a brain structure called the choroid plexus are linked to the risk of developing dementia in the future. Researchers discovered that larger choroid plexus size and lower MRI signal intensity might indicate higher dementia risk, but these changes do not alone predict the disease.Key Facts
- The choroid plexus helps produce cerebrospinal fluid and keeps the brain's environment stable.
- Researchers studied brain MRI scans and health data from more than 45,000 middle-aged adults.
- Older people tended to have a bigger choroid plexus and lower MRI signal intensity in that area.
- Larger choroid plexus volume was associated with a higher chance of developing dementia later.
- Higher choroid plexus signal intensity was linked to a lower dementia risk.
- These brain changes might be part of broader brain aging and memory-related changes.
- Current tools detect dementia after symptoms or damage appear, but this research aims to identify risk earlier.
- The study does not provide a standalone test to predict dementia but highlights a new possible risk marker.
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