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VA to run trial of GLP-1 drug to treat alcohol abuse

VA to run trial of GLP-1 drug to treat alcohol abuse

Summary

The Department of Veterans Affairs (VA) has started a clinical trial to test if semaglutide, a drug normally used to treat diabetes and help with weight loss, can also reduce alcohol abuse in veterans. The study will involve over 600 veterans at 18 VA medical centers and will last 28 weeks.

Key Facts

  • The drug being tested is semaglutide, which belongs to a group called GLP-1 drugs.
  • GLP-1 drugs may reduce cravings and could potentially help treat alcoholism and other addictions.
  • The study will include more than 600 veterans from 18 VA medical centers.
  • Participants will get weekly injections of either semaglutide or a placebo for 28 weeks.
  • Researchers will track changes in alcohol consumption, health, and quality of life.
  • About 14% of veterans have alcohol abuse problems, higher than the roughly 10% in the general population.
  • Veterans who served in combat or have traumatic brain injuries are at greater risk of alcohol abuse.
  • The VA aims for this research to benefit veterans by finding new treatment options for alcohol use disorders.
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