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Scientists Find Hidden Alzheimer's Brain Buildups That May Appear Early

Scientists Find Hidden Alzheimer's Brain Buildups That May Appear Early

Summary

Scientists discovered a new type of brain plaque called "mitochondrial plaques" that may appear early in Alzheimer's disease. These plaques are different from the well-known beta-amyloid plaques and could lead to new ways to treat or prevent Alzheimer's.

Key Facts

  • Researchers at the University of Minnesota found "mitochondrial plaques" in both lab models and human brains.
  • Mitochondrial plaques may appear before traditional beta-amyloid plaques in Alzheimer's.
  • These plaques contain high levels of amyloid precursor protein, which is linked to beta-amyloid plaques.
  • Unlike beta-amyloid plaques outside brain cells, mitochondrial plaques affect neurons directly.
  • The discovery may change how scientists understand the start and progress of Alzheimer's disease.
  • Experts say more research is needed to confirm the role of mitochondrial plaques in the disease.
  • The study highlights the potential role of mitochondria (parts of cells that produce energy) in Alzheimer's development.
  • Understanding these plaques could lead to new strategies to slow or prevent Alzheimer's disease.
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