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Overlooked Body Function May Predict Faster Alzheimer's, Study Finds

Overlooked Body Function May Predict Faster Alzheimer's, Study Finds

Summary

A new study found that lower heart function may lead to faster brain shrinkage in older adults who carry a gene linked to Alzheimer’s disease. Researchers followed more than 700 adults for up to 11 years and saw that those with lower cardiac output and the APOE-e4 gene experienced more brain volume loss in key areas related to Alzheimer’s.

Key Facts

  • The study involved 756 adults aged 50 to 92, followed for up to 11 years.
  • Cardiac output measures how much blood the heart pumps.
  • Lower cardiac output was linked to smaller brain volumes, especially in areas affected by Alzheimer’s.
  • The APOE-e4 gene is a known genetic risk factor for Alzheimer’s disease.
  • The study showed an association, not proof that lower heart function causes brain shrinkage.
  • Brain imaging and heart tests were used to track changes over time.
  • Results suggest even mild heart function declines can affect brain health in people at genetic risk.
  • The research highlights the connection between heart health and brain health.
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