Estrogen Therapy May Hold Clues to Lower Dementia Risk in Women
Summary
A new study from Stanford Medicine found that women who used estrogen-only hormone therapy after menopause had lower chances of developing dementia and showed fewer signs of Alzheimer’s disease in their brains. The research looked at clinical data and brain autopsies from over 21,000 women aged 50 and older.Key Facts
- The study involved more than 21,000 women aged 50 and older.
- Women who used estrogen-only hormone therapy had 35% lower odds of Alzheimer’s disease-related brain changes found at autopsy.
- Those using estrogen therapy also had 39% lower odds of being diagnosed with dementia.
- The research analyzed data from two large Alzheimer’s research databases.
- The study looked at clinical diagnoses, brain imaging, biomarkers, and autopsy results.
- Estrogen therapy users showed less memory and functional decline.
- The study was observational and does not prove hormone therapy prevents dementia.
- Experts note that women who chose hormone therapy often had other advantages like better healthcare access.
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