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FDA gives expedited approval to new groundbreaking pancreatic cancer drug

FDA gives expedited approval to new groundbreaking pancreatic cancer drug

Summary

The FDA has quickly approved a new pill called daraxonrasib for the most common type of pancreatic cancer. This drug helps block a protein mutation that causes tumor growth, and patients taking it lived almost twice as long as those who received chemotherapy.

Key Facts

  • The drug daraxonrasib was given expedited approval by the FDA.
  • It targets a mutated protein found in over 90% of pancreatic cancer cases.
  • Patients using daraxonrasib lived a median of 13.2 months, compared to 6.7 months with chemotherapy.
  • The drug is sold under the brand name Rasonque by Revolution Medicines.
  • Pancreatic cancer is hard to detect early and has a low five-year survival rate of 13%.
  • The drug acts like “molecular glue” to bind to mutated Ras proteins, which were previously considered untreatable.
  • The FDA approved the drug more than six months ahead of schedule.
  • Revolution Medicines is also testing this drug technology on other cancers such as lung cancer.
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