Daily Pill May Slow Progression of Type 1 Diabetes-'Really Exciting Step'
Summary
A study showed that a daily pill, baricitinib, can slow the progression of type 1 diabetes, but this benefit stops once the treatment ends. Baricitinib helps preserve insulin production and is already used for some autoimmune diseases. When the pill is discontinued, participants' insulin production decreases, making disease management similar to those not taking the pill.Key Facts
- Baricitinib is a pill initially prescribed for rheumatoid arthritis and alopecia.
- A trial in Australia tested baricitinib on people newly diagnosed with type 1 diabetes.
- The pill preserved insulin production for 48 weeks but not after stopping.
- Type 1 diabetes occurs when the immune system attacks insulin-producing cells.
- Baricitinib is a Janus kinase (JAK) inhibitor that reduces immune system overactivity.
- The study included 91 participants aged 10 to 30, with assessments at multiple points.
- The trial found baricitinib to be safe, with no side effects from the drug.
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