Scientists Studied 1,300 Cancer Patients, Then Found a Pattern in the Gut
Summary
Scientists studied stool samples from 1,364 cancer patients and found specific patterns in gut bacteria linked to different types of cancer. They also discovered differences in gut bacteria in younger patients with early-onset colorectal and breast cancers and saw potential for using gut bacteria to predict treatment side effects.Key Facts
- Researchers analyzed gut microbiomes from 1,364 cancer patients with various cancers, stages, and treatments.
- Unique gut bacteria patterns were linked to five major cancer groups.
- Younger patients (50 and under) with colorectal cancer had more lactate and more of the bacterium Veillonella parvula.
- Younger breast cancer patients showed changes in 64 bacterial types and lower levels of primary bile acids.
- Gut bacteria patterns could predict which patients might get diarrhea from the chemotherapy drug 5-fluorouracil (5-FU).
- This predictive pattern was not seen with the chemotherapy drug carboplatin.
- The study found bacteria linked to survival outcomes in colorectal, liver, ovarian, prostate cancers, and melanoma.
- Researchers say more studies are needed before using gut microbiome tests in regular cancer care.
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