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Huntington's disease successfully treated for first time

Huntington's disease successfully treated for first time

Summary

Doctors have successfully treated Huntington's disease for the first time, slowing its progression by 75%. The new treatment, a type of gene therapy, is performed during a long brain surgery and aims to give patients more years of quality life.

Key Facts

  • Huntington's disease affects brain cells and acts like a mix of dementia, Parkinson's, and motor neurone disease.
  • The new gene therapy treatment was tested in the UK, led by Professors Ed Wild and Sarah Tabrizi.
  • The treatment involves a 12 to 18-hour brain surgery using precise techniques.
  • Patients who received the treatment saw a 75% reduction in the disease's progression rate.
  • The therapy helps reduce the toxic protein levels that damage brain cells in Huntington's disease.
  • The treatment could allow patients to live longer with better quality of life but is expected to be expensive.
  • Huntington's disease is genetic; if a parent has the gene, there’s a 50% chance their child will too.
  • The goal is to prevent symptoms from appearing by using a virus to deliver therapeutic DNA into the brain.
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