Same-day test helps doctors detect hidden infections in critically ill children
Summary
A new same-day test called metagenomic testing can detect hidden and drug-resistant infections in very sick children. This test looks at all the genetic material in a sample to find bacteria, viruses, and fungi, helping doctors choose the right treatment faster and more accurately.Key Facts
- Metagenomic testing was used on over 100 critically ill children at Great Ormond Street Hospital (GOSH) in London.
- The test finds all types of germs in one sample, unlike older methods that look for specific infections.
- It helped doctors identify unseen drug-resistant infections, leading to better treatment decisions.
- In one case, the test saved 10-year-old Willow Crowther’s life by detecting a resistant infection early.
- Around 90% of bacteria and viruses and 100% of fungi in samples were identified by metagenomics.
- The test influenced doctors’ decisions in 25% of cases, including antibiotic choices.
- It found 50 germs not found by standard tests, which may help track new or pandemic threats.
- Metagenomic testing is being expanded to about 30 intensive care units across the UK.
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