Pattern Linked to Higher Alzheimer’s Odds, Study Finds
Summary
Researchers found that a certain repeated DNA sequence is linked to higher chances of having Alzheimer's disease. The study showed that Chinese people with many repeats of a gene sequence called CCG had about double the odds of having Alzheimer’s compared to those with fewer repeats, with a weaker link found in Europeans.Key Facts
- The study focused on the gene FAM193B and a repeated DNA sequence called CCG.
- People with 18 or more repeats of CCG had twice the odds of Alzheimer’s compared to those with 11 or fewer repeats.
- The research involved over 3,000 Chinese participants and data from the UK Biobank with mostly European participants.
- The link was stronger in Chinese participants than in Europeans.
- Alzheimer's disease risk is influenced by a mix of genetics, lifestyle, and environment.
- This research looks beyond single DNA changes to repeated sequences, which may explain more about Alzheimer’s risk.
- Experts believe these findings could help improve Alzheimer's risk prediction and possibly point to new treatments.
- The study was published in the journal Nature Neuroscience on October 12.
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