Scientists Gave Breast Cancer Survivors a Supplement—Then Something Changed
Summary
A small UCLA study found that breast cancer survivors who took oxaloacetate for eight weeks reported improved cognitive-function scores and less fatigue. The study had 18 participants and no comparison group, so it cannot establish that the supplement caused the changes or confirm its effectiveness.Key Facts
- The study was published October 20 in JCO Oncology Advances.
- Researchers enrolled 18 women with early-stage breast cancer who were at least 12 months past primary treatment and had no evidence of active or recurrent disease.
- Participants took 500 milligrams of oxaloacetate twice daily for eight weeks.
- The group’s average score on a self-reported cognitive-impairment scale rose from 29.1 to 55.5; scores below 54 indicate impairment.
- The 16 participants who continued taking the supplement also reported improved fatigue-related symptoms.
- Researchers reported improvement in physical functioning and small, statistically non-significant changes in insomnia, anxiety, and depression.
- Two participants stopped the supplement because of adverse effects; the article does not provide further details about those effects.
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