Summary
Category: technology
Scientists at Yale used advanced 3D imaging technology to understand how Legionnaires' disease bacteria infect human cells. They discovered a complex structure within the bacteria and identified the proteins involved, which could assist in developing new treatments. This research could lead to better ways to combat the disease, which is increasingly common in the U.S.
Key Facts
- Yale scientists used a technology called cryo-electron microscopy (cryo-EM) to study Legionnaires' disease bacteria.
- Legionnaires' disease is a severe type of pneumonia and is often caught from sources like air conditioning systems and hot tubs.
- The disease has been on the rise in the U.S., affecting about 10,000 people each year.
- Researchers mapped out over 76,000 particles to understand the bacteria's complex infection system.
- They identified 20 different proteins, including one called DotA, crucial for the bacteria's function.
- The findings could help develop treatments that prevent bacteria from becoming resistant to antibiotics.
- Antibiotic resistance is a major global health threat, according to the World Health Organization.
