Stimulant overdoses on the rise as opioid deaths decline, but treatment is complex
Summary
CDC data show stimulant-involved overdoses rising in parts of the United States as fentanyl deaths fall. Experts say stimulant overdoses can be harder to recognize than opioid overdoses, and urge bystanders to call 911, watch for urgent symptoms and reduce stimulation while help is on the way.Key Facts
- Fentanyl-involved overdose deaths fell to pre-pandemic levels nationally in 2025, according to provisional CDC data.
- Deaths involving cocaine rose in 13 states, while deaths involving methamphetamine rose in eight states.
- Arizona has reported record highs in nonfatal stimulant overdoses.
- Stimulant overdoses can cause heart attacks, strokes, seizures, shortness of breath and dangerous overheating.
- Experts say stroke signs such as face droop, weakness, vision changes or speech difficulty require immediate medical attention.
- Bystanders should call 911 for an overdose; naloxone may help if opioids are also involved.
- While waiting for an ambulance, responders recommend reducing noise, bright lights and crowds around the person.
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