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Cardiovascular Drugs Show Promise Against Most Common Liver Disease

Cardiovascular Drugs Show Promise Against Most Common Liver Disease

Summary

Researchers from the University of Barcelona found that using two drugs, pemafibrate and telmisartan, together may help treat fatty liver disease, also known as MASLD. This condition affects about a quarter of U.S. adults. The study showed that this drug combination could lower fat in the liver and reduce related heart risks in laboratory tests.

Key Facts

  • The University of Barcelona conducted the study on fatty liver disease (MASLD).
  • MASLD is the most common chronic liver disease in the U.S., impacting about 25% of adults.
  • The study tested pemafibrate and telmisartan, which are already used for other health issues.
  • Pemafibrate is used in Japan to treat blood fat issues, while telmisartan is a blood pressure medicine used widely, including in the U.S.
  • The drugs were tested in animal models and showed a reduction in liver fat.
  • The study suggests that these drugs could be used in the early stages of MASLD to prevent progression.
  • Lifestyle changes are important for MASLD treatment, but they can be challenging for patients to stick to.
  • Early diagnosis and treatment of MASLD can prevent severe complications and lower mortality rates.

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