Summary
Scientists successfully reversed Alzheimer’s disease in mice by improving the function of the brain's blood vessels using nanotechnology. The new approach uses nanoparticles to clear waste proteins and restore the brain’s natural defenses, potentially opening a new path for Alzheimer’s treatment.
Key Facts
- Researchers worked at the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital of Sichuan University (WCHSU).
- The study used nanoparticles as drugs to clear amyloid-β proteins, which are linked to Alzheimer’s disease.
- This method restored the normal function of the blood-brain barrier, which protects the brain.
- Mice treated with these nanoparticles showed a significant reduction in amyloid-β levels within an hour.
- The mice regained behaviors similar to healthy ones months after treatment.
- The study highlights the importance of vascular health in Alzheimer’s disease.
- No harmful effects were observed in the mice receiving the treatment.
- The treatment could potentially improve existing Alzheimer’s therapies by restoring the brain’s defenses.
