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Chronic fatigue is not in your head - it's in your blood, say experts

Chronic fatigue is not in your head - it's in your blood, say experts

Summary

University of Edinburgh researchers found differences in the blood of people with ME/CFS (myalgic encephalomyelitis or chronic fatigue syndrome) compared to healthy individuals. The study suggests these differences could help create a future blood test for diagnosing ME/CFS. Some experts caution that the study's claims should not overstate its findings.

Key Facts

  • ME stands for myalgic encephalomyelitis, also known as chronic fatigue syndrome (CFS).
  • The study used data from the UK Biobank, comparing 1,455 ME/CFS patients with 131,000 healthy people.
  • Researchers found consistent blood differences in ME/CFS patients linked to inflammation, insulin resistance, and liver disease.
  • The condition's main symptom is post-exertional malaise, which is severe fatigue after minimal physical activity.
  • Other symptoms include pain, brain fog, and tiredness that does not improve with rest.
  • The study aims to develop a blood test for diagnosing ME/CFS in the future.
  • The research considered over 3,000 blood biomarkers, taking age, sex, and activity levels into account.
  • Critics say the study should not overstate its importance as both physical and mental illnesses can show blood differences.
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