Summary
Researchers from Duke Health and the University of Minnesota found that a simple blood test can predict the short-term survival of older adults by analyzing small RNA molecules called piRNAs. These molecules proved to be stronger predictors of survival than age or lifestyle habits. The study suggests that piRNAs could eventually help guide interventions for healthy aging.
Key Facts
- A blood test can predict whether older adults are likely to live at least two more years.
- The study involved researchers from Duke Health and the University of Minnesota.
- The test focuses on small RNA molecules known as piRNAs.
- Lower levels of specific piRNAs are linked to longer survival.
- Researchers used AI and machine-learning to analyze data from over 1,200 blood samples.
- The method was validated in a second group of older adults.
- piRNAs outperformed other health indicators like age and lifestyle for predicting short-term survival.
- Future research will explore how lifestyle or medications might change piRNA levels.
