A new study from Sweden found that breast cancers with low to intermediate levels of estrogen receptors (ER) behave differently than those with high ER levels. The researchers suggest that classifying breast cancer by ER levels as a spectrum, rather than a simple positive or negative, could improve treatment decisions and patient outcomes.
Key Facts
Breast cancer cells can have receptors for hormones like estrogen (ER) and progesterone (PR), which influence treatment options.
Cancers are usually classified as ER-positive or ER-negative based on the presence of estrogen receptors.
The study analyzed data from over 75,000 women in Sweden with HER2-negative breast cancer.
Tumors with 10%-29% ER expression had survival rates and features closer to ER-negative cancers than strongly ER-positive ones.
Patients with ER expression between 10% and 59% had worse survival than those with high ER levels.
Combining chemotherapy with hormone therapy improved survival in patients with intermediate ER expression compared to hormone therapy alone.
Researchers suggest ER should be reported as a percentage and used as a continuous measurement for treatment decisions.
More research is needed to apply these findings in clinical practice and explore other factors like progesterone receptors.
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Violence by Israeli settlers in the occupied West Bank is increasing and may reach record levels this year. Human rights groups say these settlers are moving into new areas and attacks on Palestinians have risen alongside the growth of Israeli settlements, which are illegal under international law.
Key Facts
Violence by Jewish settlers in the West Bank is on the rise.
Attacks on Palestinians by settlers have increased under the current Israeli government.
Israeli settlements in the West Bank are expanding rapidly.
These settlements are considered illegal under international law.
Many settler attacks on Palestinians get little media coverage.
The BBC tracked settler violence incidents over one recent week.
Human rights groups warn that settler violence is spreading into new parts of the West Bank.
The report is part of ongoing coverage of tensions between Israelis and Palestinians in the region.
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Anil Goel, a 67-year-old man from Northern Virginia, went missing after severe floods and mudslides swept away a border checkpoint on the Nepal-Tibet border. He was part of a group crossing from Nepal to Tibet on a pilgrimage when the disaster struck, and rescue efforts continue as many remain missing.
Key Facts
Anil Goel was at the Rasuwagadhi immigration checkpoint near the Nepal-Tibet border when floods and mudslides destroyed the area.
About 10 Americans, including Goel, were at the checkpoint on August 26, 2026, just before the disaster.
Goel’s family received a photo showing his group at the checkpoint about 35 minutes before the floods.
His visa was approved at 8:35 a.m. local time, shortly before the area was hit by the flood.
The disaster was caused by the collapse of a rock ledge and a Himalayan glacier upstream.
Goel was on a hiking and religious pilgrimage trip to Mount Kailash, a sacred mountain in Tibet.
He had visited Nepal many times before for trekking and loved the region.
Rescue operations are still ongoing, with concerns about a swollen glacial lake that could cause more flooding.
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A study analyzing over 64,000 adults found that people who ate less sugar during their first 1,000 days after conception had lower rates of several cancers and aged more slowly at a biological level. The research used the natural experiment of sugar rationing in the UK in the early 1950s to compare those exposed to lower sugar intake with those who were not.
Key Facts
The study used data from 64,761 adults in the U.K. Biobank.
Sugar rationing in the UK ended in September 1953, doubling daily sugar consumption from about 40g to 80g.
Adults who had reduced sugar exposure in their first 1,000 days showed lower risks of several cancers, including liver, rectal, lung, prostate, and breast cancers.
The risk of liver and intrahepatic bile duct cancers was 69% lower in those exposed to sugar rationing.
Lower sugar intake early in life may lead to healthier eating habits that last into adulthood.
Researchers suggest both lasting biological effects and long-term behavior changes may explain the health benefits.
The first 1,000 days after conception are critical for developing food preferences and biological development.
Participants with lower early sugar exposure had longer telomeres, a marker linked to slower aging.
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Jordan Bardella, leader of France’s far-right National Rally party, will speak at the Reform UK party conference in Birmingham to strengthen international ties ahead of Marine Le Pen’s 2024 French presidential run. Bardella and Reform UK leader Nigel Farage share similar anti-immigration views and plan future cooperation if both lead their countries.
Key Facts
Jordan Bardella is the leader of France’s far-right National Rally party.
He will speak at Reform UK’s party conference in Birmingham next week.
Marine Le Pen, Bardella’s party’s presidential candidate for 2024, is leading in polls.
Le Pen is appealing a court ruling that found her guilty of embezzling European parliament funds.
Le Pen plans to run for president with Bardella as her prime minister candidate.
Bardella and Nigel Farage, leader of Reform UK, have discussed anti-immigration cooperation.
Bardella supports closer police work between London and Paris on migrant crossings but wants migrants sent back to their home countries.
Farage has been under investigation for not declaring large financial gifts during elections.
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Four men pleaded guilty to setting fire to four ambulances serving the Jewish community in north-west London. The attack happened in March 2026 and caused about £1 million in damage. The vehicles belonged to the charity Hatzola, and the incident is believed to be a targeted attack.
Key Facts
Four men aged 18 to 20 admitted to destroying or damaging property by reckless arson.
The fire destroyed four ambulances in Golders Green, London.
The attack took place in the early hours of 23 March 2026.
The ambulances belonged to the Jewish community charity called Hatzola.
Authorities consider the attack was aimed specifically at the Jewish community.
Damage caused by the fire is estimated at £1 million.
Sentencing for the four men is expected in spring 2027.
The news is still developing and more details will be released later.
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Oslo's Mayor Anne Lindboe has postponed her wedding after the death of Norway's King Harald V. The king died after a 35-year reign, and his son Haakon VIII became the new monarch on the same day.
Key Facts
Oslo's Mayor Anne Lindboe was engaged to Pål Sandvid and planned to marry on the day King Harald V died.
The wedding was postponed due to the king's passing, and no new date has been set.
King Harald V died at a hospital in Oslo while being treated for a rare blood condition.
Harald reigned for 35 years and modernized Norway's monarchy.
He married Queen Sonja, who was a commoner, breaking royal tradition.
The late king died a day before his 58th wedding anniversary.
Public memorials were held outside the Royal Palace in Oslo with flowers and tributes.
Norway’s Prime Minister and Britain’s King Charles III expressed grief and respect for King Harald V.
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A German court sentenced an 81-year-old man named Hans S. to life in prison for the 1994 rape and murder of Amy Lopez, a 24-year-old American tourist. Advances in DNA technology helped the police identify and convict him more than 30 years after the crime.
Key Facts
Amy Lopez was found dead near Ehrenbreitstein Fortress in Koblenz, Germany, with stab wounds, head injuries, and signs of strangling.
The man convicted, Hans S., was arrested in 2026 at a retirement home after DNA from a saliva sample matched DNA found on Lopez’s clothing.
Hans S. had a previous conviction from 1999 for attempting to rape a 16-year-old girl.
The court said Hans S. lured Lopez on a secluded path under the pretense of showing her the way to a youth hostel before attacking her.
Police investigated about 1,600 DNA samples before finding the match that linked Hans S. to the crime.
A reward and TV coverage in 2024 helped bring in tips that led to the arrest.
Lopez's family participated in the trial as co-plaintiffs.
The court emphasized the "particular gravity of guilt," making early release for Hans S. less likely.
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Gatwick Airport lost water supply after a main water pipe burst in nearby Horley, affecting both airport terminals. SES Water is working to fix the problem, and flights are continuing as usual despite some closed toilets and limited restaurant services.
Key Facts
A burst water main in Horley caused parts of Gatwick Airport to lose water supply.
Both the North and South Terminals experienced water issues, with North Terminal toilets closed.
Food outlets in the North Terminal stayed open but only for seating, not serving food.
SES Water is repairing the burst pipe and apologizing for the disruption.
This is the second water supply problem at Gatwick in recent weeks; a power failure in July also caused water outages.
Passengers reported frustration due to lack of water and limited communication about the issue.
Despite water problems, flights at Gatwick Airport have not been affected.
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Brussels is experiencing a sharp rise in shootings linked to drug gangs, with over 100 incidents reported in 2025 alone. Drug dealing and violence have increased, turning some city neighborhoods into dangerous areas similar to other troubled European cities.
Key Facts
There were more than 100 drug-related shootings in Brussels in 2025 and over 65 in 2026 so far.
Shootings and violence are frequent near Brussels South, including areas close to the Midi train station.
Drug gangs openly sell drugs like crack in busy public places, attracting many buyers.
A single successful drug-selling spot can earn dealers up to €50,000 ($58,000) per day.
Police report increased gang violence and the use of heavy weapons like AK-47s.
Young people as young as 12 are involved in shootings, often receiving little money for dangerous tasks.
A police station was attacked recently, marking a rise in violence against law enforcement.
Authorities are working to prevent Brussels from becoming as violent as cities like Marseille, which struggles with similar gang conflicts.
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Céline Dion has arrived in Paris to prepare for a series of 16 sold-out comeback concerts starting in September and October. She announced these shows after a long break caused by health issues linked to Stiff Person Syndrome, a rare autoimmune disorder.
Key Facts
Céline Dion landed in Paris two weeks before her first comeback concert.
She described Paris as her "second home" and thanked fans for their support.
The singer will perform 16 shows in Paris this autumn, all of which sold out quickly.
Her last full concerts took place in 2020 before she paused due to health problems.
Dion revealed in 2022 that she has Stiff Person Syndrome, an incurable autoimmune illness.
The ticket demand for her comeback was very high, similar to big events like Taylor Swift’s 2024 tour.
Dion previously appeared at the Paris Olympics opening ceremony in 2024.
She had to cancel shows due to the Covid pandemic and her illness.
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Celine Dion arrived in Paris to prepare for her comeback concerts after a long break due to health problems. She is scheduled to perform 16 sold-out shows in September and October in the French capital.
Key Facts
Celine Dion arrived in Paris two weeks before her first comeback concert.
She will perform 16 concerts in Paris starting in September and October.
Her last full concert tour was in 2020.
She announced the comeback concerts after a long break caused by health issues.
Celine Dion has been diagnosed with Stiff Person Syndrome, a rare autoimmune disorder.
Her tickets sold out quickly, with demand similar to major artists like Taylor Swift.
Fans greeted her warmly at the Royal Monceau hotel near the Champs-Elysees.
She performed at the opening ceremony of the Paris Olympics in 2024.
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At least 17 companies linked to illegal Israeli settlements in the West Bank hold UK public contracts worth over £2.1 billion ($2.85 billion). UK politicians and experts are concerned that these contracts may breach international law, especially after a UN court called Israel’s occupation unlawful and urged other countries not to support it.
Key Facts
17 companies tied to illegal Israeli settlements have UK public contracts totaling more than £2.1 billion.
These contracts cover services like road maintenance, transport, emergency services, and driving licensing.
Five major corporate groups involved include Motorola Solutions, Heidelberg Materials, Egis, CAF, and Fosun International.
Motorola’s British subsidiary Airwave Solutions holds the majority of the contract value, over £1.7 billion.
The UN Human Rights Office had previously named these companies for their involvement in illegal settlements.
The International Court of Justice ruled in July 2024 that Israel’s presence in the occupied territories is illegal and must end quickly.
The ICJ also said other countries should not help maintain the situation created by Israel’s occupation.
Critics say the UK government may be breaking international law by continuing to buy services from these companies.
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Flash floods in Nepal and Tibet have killed at least 538 people and left more than 1,500 missing, including many foreign tourists. Families of 33 missing British nationals are traveling to Nepal to find their loved ones amid fears of further floods caused by rising lakes formed by debris.
Key Facts
Flash floods struck Nepal and Tibet, killing at least 538 people and leaving over 1,500 missing.
Among the missing are hundreds of foreign tourists, including 33 British citizens.
Families of missing Britons are rushing to Nepal, especially the Rasuwa district, to search for them.
Power and communication lines are down in the flood-hit areas, making communication difficult.
Nepal and Chinese authorities warned of a second wave of flooding due to lakes formed by debris blocking rivers.
Rescuers paused their searches, and residents in affected areas were told to evacuate.
Some missing Britons were part of pilgrimage groups and trekking tours near Mount Kailash and the Nepal-Tibet border.
Tour operators and families have reported multiple cases of missing British tourists caught in the floods.
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Nearly 500 migrants arrived in the UK in one day by crossing the English Channel in small boats, the first crossings after a 10-day pause. Overall, fewer people have crossed by small boats this year compared to last year, but the number of people in each boat has increased, making the journeys more dangerous.
Key Facts
Seven boats carrying 494 people arrived in the UK on one day after no arrivals for 10 days.
From January to August 2026, about 15,897 people crossed the Channel by small boats, a 45% drop from the previous year.
Since 2020, small boats are the most common way people are caught entering the UK illegally.
Most people arriving by small boats ask for asylum, which lets them stay while their requests are reviewed.
The average number of people per boat has more than doubled since 2021, increasing risks.
At least 84 people died trying to cross the Channel in 2024, according to the United Nations.
People from Eritrea made up 18% of arrivals between July 2025 and June 2026.
Over 2,300 small boat arrivals were identified as potential victims of human trafficking or modern slavery in 2025.
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President Donald Trump signed an executive order to rename Lake Ontario as "Lake America" during a trade dispute with Canada. This follows a similar previous action where he renamed the Gulf of Mexico the "Gulf of America" amid a disagreement with Mexico.
Key Facts
President Trump renamed Lake Ontario as "Lake America" by executive order.
The renaming happened during a trade conflict between the U.S. and Canada.
This is not the first time President Trump has renamed a body of water amid trade disputes.
Last year, President Trump renamed the Gulf of Mexico the "Gulf of America" during a dispute with Mexico.
The move is part of a series of actions related to tariffs and trade disagreements.
The renaming reflects tensions between the U.S. and neighboring countries over trade policies.
The official names of these bodies of water have not changed in international or geographic registries.
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The article discusses how many politicians now use rude or offensive language in public. It suggests that this behavior harms respectful conversation and the quality of public discussion.
Key Facts
Politicians often speak with crude or offensive language in public.
They may believe this makes them seem more real or passionate.
The article argues this actually shows a lack of self-control.
It also says this behavior damages respectful public talk.
The overall tone warns about the negative effects on society’s conversations.
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Jake Reiner gave his first interview after his parents, filmmaker Rob Reiner and Michele Singer Reiner, were found dead in their Los Angeles home in December. His brother Nick Reiner was charged with their murders and has pleaded not guilty, while Jake expressed deep shock and sadness over the loss.
Key Facts
Rob Reiner, a filmmaker known for movies like The Princess Bride, and his wife Michele were found dead from apparent stab wounds in Los Angeles.
Their 32-year-old son Nick Reiner has been charged with two counts of first-degree murder and pleaded not guilty.
If convicted, Nick could face the death penalty, but prosecutors have not confirmed if they will seek it.
Jake Reiner, 35, spoke for the first time publicly about the tragedy, sharing his feelings of shock, anger, and grief.
Another sibling, Romy Reiner, 28, discovered their father’s body and called 911.
Jake said his parents always tried to help Nick, who struggled with addiction and mental health issues.
The film Being Charlie, directed by Rob and written by Nick, was loosely based on Nick’s life.
Nick has been blocked from accessing a $1.6 million trust fund set up for him due to a law preventing accused killers from benefiting financially from their victims.
Nick Reiner’s pretrial hearing is scheduled for September 15.
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Qatar’s minister of state visited Libya and promised to support efforts to end the country’s political division. The visit included talks with a key Libyan military leader, focusing on backing a political agreement and promoting national unity. Libya faces challenges in holding elections and achieving stability due to deep political splits.
Key Facts
Qatar’s Minister of State Mohammed bin Abdulaziz al-Khulaifi visited Benghazi, Libya.
He met Khalifa Haftar, commander of the Libyan National Army aligned with the eastern government.
Libya is divided between the Tripoli-based government and the Haftar-backed eastern administration since 2014.
Qatar supports Libya’s unity, sovereignty, and ongoing dialogue for political reconciliation.
Libya recently agreed on a preliminary election pact meant to end political division within 24 months.
The agreement involves members from both Libya’s eastern and western political bodies but faces issues of exclusion and mistrust.
The United Nations considers the deal an important step but acknowledges challenges in implementation.
Experts note gaps between those who signed the pact and the authorities who must carry it out, as well as unclear interim governance plans.
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A Dutch court sentenced Eugene N, a Rwandan man, to life in prison for his role in the 1994 genocide in Rwanda. He was found guilty of war crimes and genocide for attacking Tutsi communities and killing thousands in a stadium.
Key Facts
Eugene N was sentenced to life in prison by a court in The Hague, Netherlands.
He was convicted for actions during the 1994 Rwandan genocide, where more than 800,000 people, mostly Tutsis, were killed.
He helped attack two Tutsi communities and took part in a mob that killed around 3,000 people sheltering in a stadium in Mbazi.
Eugene N directed attackers to kill everyone and threw a grenade into a crowd of victims.
He fled the Netherlands in 1998 but later became a Dutch citizen.
Rwanda requested his extradition in 2014, but Dutch law prevents handing over its citizens.
The trial started in 2020, with more than 30 witnesses questioned before his arrest in 2024.
Eugene N denied involvement and said he tried to stop the violence; his lawyers described him as a broken man.
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