Scientists have discovered two enzymes, PDIA1 and PDIA5, that help prostate cancer cells resist treatment. Blocking these enzymes can potentially lead to more effective treatments, especially for advanced prostate cancer. The discovery may also enhance existing drugs and is currently showing positive results in lab studies.
Key Facts
Scientists identified enzymes PDIA1 and PDIA5 as key to prostate cancer cell growth and survival.
Blocking these enzymes causes instability in the androgen receptor (AR), a protein that fuels cancer growth.
This process has led to cancer cell death and tumor reduction in lab cell and animal studies.
Prostate cancer is the second-leading cause of cancer death in American men.
Researchers found combining enzyme-blocking drugs with the drug enzalutamide improved treatment results.
The enzymes help cancer cells manage stress and maintain energy, making them targets for treatment.
Current drugs targeting these enzymes require further development for safety and effectiveness in humans.
California Governor Gavin Newsom signed new laws focusing on protecting children who use chatbots and AI tools. These laws require chatbots to have safety protocols and ensure minors know they are interacting with a computer program, not a human.
Key Facts
Governor Gavin Newsom signed several new bills related to AI and chatbots.
The new laws focus on protecting children using AI tools online.
Chatbots must have protocols for dealing with content about suicide or self-harm.
Minors will receive a reminder every three hours that the chatbot is not a human.
Additional bills include age verification and warning labels for social media.
There are also new requirements for transparency from AI companies, signed last month.
These measures aim to regulate while still encouraging tech innovation.
California Governor Gavin Newsom signed a new law, Senate Bill 243, to protect children from potential harm when using AI-powered chatbots. The law sets rules for how chatbots should interact with minors, specifically aiming to prevent exposure to harmful content and address mental health risks. The bill will take effect on January 1, 2026.
Key Facts
Senate Bill 243 was signed by California Governor Gavin Newsom.
The law is the first of its kind in the U.S., focused on AI chatbot interactions with minors.
It prohibits chatbots from showing sexual content to minors.
Chatbots must alert users they are not speaking to a human and repeat this every three hours.
Operators need to report instances of suicidal thoughts detected during chatbot interactions.
Families affected by violations of this law can take legal action.
The bill will be effective starting January 1, 2026.
Some groups are concerned about the delay in required reporting to the Office of Suicide Prevention, which starts July 1, 2027.
More than 130,000 Vodafone customers in the UK experienced service disruptions on Monday. Many users had trouble with their broadband and mobile network, and some could not access Vodafone's website and app.
Key Facts
Over 130,000 Vodafone customers reported outages across the UK.
The outage affected both broadband and mobile network services.
Downdetector, a site that tracks web outages, recorded the reports.
Vodafone has more than 18 million customers in the UK.
Nearly 700,000 of these customers are home broadband users.
People complained about the outages on social media.
Some customers also reported difficulty accessing Vodafone's website and app.
Scientists discovered a molecular switch that boosts sperm energy, which could lead to new male birth control options without hormones and improve infertility treatments. This involves understanding how sperm generate energy needed for fertilization. The research identifies certain proteins that could be targeted for contraception.
Key Facts
Scientists found a way sperm get extra energy as they go from inactive to active.
This discovery might lead to non-hormonal male birth control pills.
Researchers tracked how sperm use glucose for energy.
A key enzyme called aldolase helps sperm convert glucose into energy.
Male contraceptives often use hormones and have side effects; this new method aims to avoid those issues.
The research also has potential for improving infertility treatments.
The study was done by Michigan State University and other institutes.
The goal is to create a reversible, on-demand contraceptive for men.
Qantas, an Australian airline, confirmed that the personal data of 5.7 million customers was leaked after a cyberattack. The data accessed included information like names and email addresses, but not sensitive financial details. Australia has introduced laws to strengthen cyber security following several data breaches.
Key Facts
Qantas reported a cyberattack that affected 5.7 million customer records.
The stolen data mainly included names, email addresses, and Frequent Flyer details.
More sensitive personal information, such as credit card details and passwords, was not affected.
The airline alerted all impacted customers about the breach in July.
The hacker group "Scattered Lapsus$ Hunters" is linked to the data leak.
Australia's Cyber Security Act 2024 aims to improve security measures and breach reporting.
Qantas has taken steps to improve security, including enhanced monitoring and staff training.
A study published in JAMA shows that preteens who use more social media score lower on reading and memory tests as they grow older. It suggests a link between increased social media use and weaker cognitive abilities, such as reading and memory, in adolescents.
Key Facts
The study looked at the effects of social media use on children aged 9 to 10 and followed them into their early teens.
Researchers used data from the Adolescent Brain Cognitive Development (ABCD) Study.
About 58% of the kids used little to no social media over the years.
Around 37% of the kids increased their social media use to about one hour daily by age 13.
Approximately 6% of the children used social media for three or more hours daily by age 13.
The study found that children using social media more performed worse on reading and memory tests.
Even kids with moderate social media use scored slightly lower than those with minimal or no use.
The study highlights concerns about even small amounts of social media use affecting learning, especially during school hours.
Meta has hired Andrew Tulloch, co-founder of Thinking Machines and a known expert in machine learning, to join its new TBD Labs unit. Meta's efforts to recruit top AI talent are ongoing as they continue to invest heavily in AI development.
Key Facts
Meta has hired Andrew Tulloch, a well-known machine learning expert.
Tulloch co-founded a company named Thinking Machines.
Tulloch will work in Meta's new TBD Labs, led by Alexandr Wang, Meta's Chief AI Officer.
Tulloch's salary package is less than a previous offer he declined.
Earlier reports suggested Meta's pay offer could have reached $1.5 billion, but Meta denied this.
Meta has invested billions in AI hiring, including $15 billion in Scale AI.
The hiring reflects Meta's ongoing interest in advancing its AI capabilities.
An AI-generated video falsely depicting Katie Porter, a Democratic candidate for California governor, engaging in violent behavior has gone viral on social media, receiving over 1 million views. The video is entirely fabricated using AI technology, which can create realistic but false images and videos of people. This incident highlights concerns about AI-generated content misleading voters and spreading misinformation.
Key Facts
An AI-generated video shows fake footage of Katie Porter attacking a journalist.
The video has been viewed more than 1.2 million times on social media.
Experts are concerned that AI technology can deceive people by creating realistic but false videos.
Katie Porter's campaign has been contacted for comment regarding the video.
AI-generated content poses challenges for voter trust in media and politics.
A similar AI-generated video of Porter throwing mashed potatoes has also been shared online.
Porter was previously involved in a legal dispute concerning allegations from her ex-husband, which she denied.
Researchers at the University of Sussex are studying stress by measuring changes in nose temperature using thermal cameras. The study found that stress causes a drop in nose temperature due to changes in blood flow, and this could help understand and manage stress better.
Key Facts
Scientists are using thermal cameras to study stress by filming changes in nose temperature.
Stress causes blood flow changes, reducing nose temperature by 3-6 degrees.
The study involved 29 volunteers who participated in stress tests.
Participants gave speeches and performed mental arithmetic to induce stress.
Most people recover quickly as their nose temperature returns to normal within minutes.
The research suggests that changes in nose temperature can indicate stress levels.
This method could help monitor stress in people unable to communicate, such as babies.
A woman from the U.K. named Teri Muncey shared her home's transformation from a minimalist "millennial gray" style to a more colorful and cozy "cottage core" aesthetic. Muncey changed her interior design by adding warm colors and vintage furniture, which gained attention when she posted about it online.
Key Facts
Teri Muncey is 38 years old and lives in the U.K.
Her home was originally styled in a minimalist "millennial gray" fashion with muted tones and clean lines.
Over eight years, Muncey shifted to a "cottage core" style with warm pink walls, secondhand furniture, and vintage decor.
She began buying secondhand and thrifted pieces, influencing her new design choices.
Muncey's style change was gradual and ongoing over the past five years.
A social media post comparing her home's old and new styles received a lot of attention and positive comments.
Many people online related to Muncey's move away from the "millennial gray" look to more unique and personal styles.
Tax breaks are encouraging data centers to set up in southern Atlanta suburbs. Some local residents are concerned about the increase in large data facilities in their communities.
Key Facts
Tax incentives are offered to attract data centers to certain areas.
Data centers require large spaces and good internet connections.
Southern suburbs of Atlanta are seeing an increase in data center facilities.
Many residents in these areas are worried about the impact of these large buildings.
The impacted areas include several Black neighborhoods.
A doctor shared insights on why millennials often feel lazy, revealing that the root cause is burnout. In a popular TikTok video, she explained that constant connection through digital technology and the pressure to handle numerous responsibilities contribute to stress and exhaustion, often mistaken for laziness.
Key Facts
The video by Dr. Sarah Nicholls has over 2.5 million views on TikTok.
Nicholls, a former emergency medicine doctor turned life coach, discussed millennial burnout.
She highlighted that millennials face stress from demanding jobs, family, and being always digitally connected.
Burnout is often misinterpreted as laziness among people in their 20s to 40s.
External stresses include financial instability and the digital age, normalizing overwork.
A survey found that 1 in 4 Americans reach peak burnout before age 30.
Burnout can lead to various health problems from ongoing stress responses in the body.
The article discusses cases where women who experienced miscarriages were still targeted with pregnancy-related advertisements on social media platforms like Facebook. These women, including Sammi Claxon and Tanya O'Carroll, found the ads distressing and have taken action against Meta, the company that operates Facebook and Instagram, leading to legal decisions about targeted advertising practices.
Key Facts
Women who searched for pregnancy information online were targeted with related advertisements.
Sammi Claxon experienced multiple miscarriages and continued to receive pregnancy ads, which she found distressing.
Tanya O'Carroll sued Facebook, leading to a change where Facebook agreed to stop targeting ads to individuals using personal data.
The UK's Information Commissioner's Office disagreed with Meta's defense that their ads do not count as direct marketing.
Meta claimed that ads were only directed at group sizes of at least 100 people.
Over 10,000 people in the UK have objected to Meta's use of their data for direct marketing.
Despite some legal changes for Tanya, many women continue to receive unwanted pregnancy-related ads.
The broader issue highlights ongoing concerns about privacy and data use in targeted advertising.
An increasing number of people are using AI tools like ChatGPT to plan vacations. These tools suggest destinations and itineraries, but users still need to verify the information themselves. Some users have found AI recommendations helpful, while others have discovered inaccuracies.
Key Facts
Alan Smith used ChatGPT to plan a holiday in northern Spain, discovering the town of Castro Urdiales.
The AI tool suggested places to visit, but Alan double-checked the suggestions online.
A report from the travel association ABTA shows that 8% of the population uses AI for travel planning, with the highest use (18%) among 25-34 year-olds.
Alan Smith made the final bookings himself, concerned about AI's ability to handle financial transactions.
Hannah Read tried using AI to plan a trip to Norway, but found the suggested ferry route didn't exist.
David Harris used AI to suggest itinerary ideas for a family trip to New York, finding it helpful to plan activities.
Users are advised not to rely solely on AI and to conduct their own research when planning trips.
Microsoft will stop supporting Windows 10 on 14 October, meaning PCs with that system will no longer receive security updates, which could make them vulnerable to attacks. Microsoft is encouraging users to upgrade to Windows 11 for free, but not all computers can run the new system. Users can also opt for Extended Security Updates for a limited time to keep receiving essential updates.
Key Facts
Microsoft will stop providing support for Windows 10 on 14 October.
Computers with Windows 10 will no longer receive security updates, increasing the risk of cyber threats.
Users are encouraged to upgrade to Windows 11 for free, though not all devices can support it.
There are over 1.4 billion devices using Windows worldwide; 43% used Windows 10 as of July 2025.
Users without compatible devices have the option to sign up for Extended Security Updates until October 2026.
Extended Security Updates will provide essential updates but not technical support or software enhancements.
The free upgrade to Windows 11 requires a Microsoft account and updated system settings.
For those who cannot upgrade, the Extended Security Updates service is available for a fee of $30 or through Microsoft Rewards points.
The article discusses the latest advances in breast cancer prevention and treatment. It covers new methods and technologies being developed to improve early detection and patient care.
Key Facts
Scientists are working on new ways to detect breast cancer earlier.
There are new technologies aimed at improving patient care during treatment.
Research is focused on finding more personalized treatment plans for breast cancer patients.
Some advancements involve using artificial intelligence (AI) to analyze medical images.
New medications are in development aimed at preventing breast cancer.
Clinical trials are ongoing to test the safety and effectiveness of these new treatments.
These advances aim to increase survival rates and improve quality of life for breast cancer patients.
Police departments across the United States are increasingly using drones powered by artificial intelligence (AI) to help with their work, from investigating crimes to delivering emergency medical supplies. The number of police and sheriff departments using these drones has increased significantly in recent years. While the technology provides new capabilities, it also raises concerns about privacy and data use.
Key Facts
Over 1,500 police and sheriff's departments were using drones by the end of 2024, a significant increase from 2018.
Cities like Miami, Cleveland, Columbus, and Charlotte have introduced new drone programs in 2023.
Drones are cheaper than helicopters, and federal and state funding often supports their cost.
After the George Floyd incident, many departments sought tech that collects data without direct officer involvement.
In Minnesota, police agencies spent over $1 million on drones in 2023, reflecting a 44% spending increase from 2022.
Drones equipped with AI can perform various tasks such as search and rescue, surveillance, and crime scene analysis.
Albuquerque police use drones to combat car theft and were among the first to receive FAA approval to operate without line-of-sight.
The effectiveness of drones relies on integrated systems for data analysis, but concerns exist about how collected data is used and shared.
A song by Olivia Dean called "Baby Steps" is trending on TikTok, capturing the feelings of solitude and independence. TikTok users have used the song in thousands of videos to express emotions related to loneliness and empowerment, especially reflecting a cultural shift among women toward embracing independence.
Key Facts
Olivia Dean's song "Baby Steps" is part of her album "The Art Of Loving," released in September.
The song has been used in over 7,000 TikTok videos, many of which have gone viral.
A specific lyric about being alone while traveling has resonated with users.
The U.S. surgeon general identified loneliness as a public health issue in 2023.
More U.S. women were unmarried or separated in 2021 than a decade ago.
TikTokers are using the song to express feelings of empowerment and resilience.
Many women are celebrating single life and personal milestones, like career achievements instead of traditional relationship milestones.
Videos featuring the song have received hundreds of thousands of views on TikTok.
The news article talks about a program called "Tech Now" that looks into how technology is changing different fields. It covers topics like using tech in making movie car stunts, discovering minerals, brain cell computers, and more. Various episodes explore how tech can help in areas like health, safety, and entertainment.
Key Facts
"Tech Now" explores how tech is used behind the scenes of movie car stunts.
One segment covers exploring a rare earth deposit in Greenland for important minerals.
Another part discusses computers made with brain cells.
The program includes a look at cloud seeding technology.
It examines tech solutions for early cancer detection and wildfire prevention.
The show covers topics like artificial intelligence, lithium mining, and smart tech from IFA Berlin.
It investigates new innovations in sports, including esports and Formula One.
Other topics include nuclear fusion, electric flights, and supercomputers in climate research.
